Hyperbaric Drug Interactions

These papers are more general reviews of the topics listed and have been selected based on searches of the Rubicon Research Repository (RRR) and questions found in online forums. They are meant to serve as a starting point for anyone interested in the contents of our collection. This is by NO means an exhaustive search or list of categories. We will continue to build on this resource as we have time so please check back with us.

Walsh (ed). (1979) Interaction of Drugs in the Hyperbaric Environment. RRR: 4252

Taylor, S; Taylor, DMcD; O’Toole, KS; Ryan, CM. (2002) Medications taken daily and prior to diving by experienced scuba divers. Journal of the South Pacific Underwater Medicine Society. 32(3) RRR: 7684

Taylor, DMcD; O’Toole, KS; Auble, TE; Ryan, CM; Sherman, DR. (2001) The psychometric and cardiac effects on pseudoephedrine and antihistamines in the hyperbaric environment. Journal of the South Pacific Underwater Medicine Society. 31(1) RRR: 7711

Walsh and Burch. (1977) The behavioral toxicity of Sudafed, Benadryl, and Dramamine under hyperbaric air. RRR ID: 4117 Note: This is an abstract, there is no article available. More available at RRR:4252

Schwartz and Curley. (1986) Transdermal Scopolamine in the Hyperbaric Environment. RRR ID: 3528

Bitterman et. al. (1991) Hyperbaric oxygen and scopolamine. RRR ID: 2573

Williams et. al. (1988) Effects of transcutaneous scopolamine and depth on diver performance. RRR ID: 2495

Arieli et. al. (1999) Effect of the anti-motion-sickness medication cinnarizine on central nervous system oxygen toxicity. RRR ID: 2307

Fowler, Hamilton, and Porlier. (1986) Effects of ethanol and amphetamine on inert gas narcosis in humans. Undersea Biomed Res. Sep;13(3):345-54. RRR ID: 3050

Walsh and Burch. (1978) Behavioral effects of the interaction of marijuana and increasing partial pressures of N2 and O2. RRR ID: 4320  Note: this is an abstract so NO paper available.

Walsh and Burch. (1977) Reduction of the Behavioral Effects of delta(9)-Tetrahydrocannabinol by Hyperbaric Pressure. (editor note: Cannabis) NMRI report ADA046749 published as: Pharmacology Biochemistry and Behavior, v7 p111-116. RRR ID: 4226

Rencricca and Coleman. (1979) Modulation of Oxygen Toxicity by Select Anti-Melanogenic Compounds. RRR ID: 3278  Note: Drugs tested include Disulfiram, D-Penicillamine, 2-Thiouracil, Isoascorbic Acid, Glutathione, Ascorbic Acid.

Nicholson and Aksenov. (2002) Review of literature evaluating the interactions of drugs and high concentrations of oxygen. RRR ID: 1086  Note: this is an abstract so NO paper available.